Fenwick’s Down the Gradient
Fenwick’s Down the Gradient podcast cuts through the noise around AI to take a thoughtful look at the real decisions shaping the AI ecosystem, one topic at a time. Instead of headlines or hype, we're focused on practical conversations about how AI is actually being developed, governed, and commercialized, from regulation and trust and safety, to investments, exits, and open-source strategy.
Episodes

Wednesday Mar 18, 2026
Wednesday Mar 18, 2026
AI is everywhere in life sciences, forcing hard questions about ownership, value, and collaboration.
In this episode of Down the Gradient, Fenwick’s Adine Mitrani and Toney Jacobson sit down with Andrew Whitehead, associate general counsel at Genentech, to discuss:
The evolving role of AI in the life sciences industry, and what has and hasn’t changed over the last five years
The realities of securing “meaningful” patent protection for AI-related inventions in life sciences
Key implications of USPTO Commissioner John Squires’ revised Inventorship Guidance for AI-Assisted Inventions
What makes a good AI partnership and red flags that might kill a deal

Thursday Jan 15, 2026
Thursday Jan 15, 2026
Fenwick’s Down the Gradient podcast cuts through the noise around AI to take a thoughtful look at the real decisions shaping the AI ecosystem, one topic at a time. Instead of headlines or hype, we're focused on practical conversations about how AI is actually being developed, governed, and commercialized, from regulation and trust and safety, to investments, exits, and open-source strategy.




